Traditional Chinese medicine herbal extracts of Cibotium barometz, Gentiana scabra, Dioscorea batatas, Cassia tora, and Taxillus chinensis inhibit SARS-CoV replication
Identifieur interne : 000C23 ( Main/Exploration ); précédent : 000C22; suivant : 000C24Traditional Chinese medicine herbal extracts of Cibotium barometz, Gentiana scabra, Dioscorea batatas, Cassia tora, and Taxillus chinensis inhibit SARS-CoV replication
Auteurs : Chih-Chun Wen [Taïwan] ; Lie-Fen Shyur [Taïwan] ; Jia-Tsrong Jan [Taïwan] ; Po-Huang Liang [Taïwan] ; Chih-Jung Kuo [Taïwan, États-Unis] ; Palanisamy Arulselvan [Taïwan] ; Jin-Bin Wu [Taïwan] ; Sheng-Chu Kuo [Taïwan] ; Ning-Sun Yang [Taïwan]Source :
- Journal of Traditional and Complementary Medicine [ 2225-4110 ] ; 2011.
Abstract
Development of anti-severe acute respiratory syndrome associated coronavirus (SARS-CoV) agents is pivotal to prevent the reemergence of the life-threatening disease, SARS. In this study, more than 200 extracts from Chinese medicinal herbs were evaluated for anti-SARS-CoV activities using a cell-based assay that measured SARS-CoV-induced cytopathogenic effect (CPE)
severe acute respiratory syndrome
coronavirus
cytopathogenic effect
traditional Chinese medicine
Url:
PubMed: 24716104
PubMed Central: 3942999
Affiliations:
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<italic>Taxillus chinensis</italic> inhibit SARS-CoV replication</title><author><name sortKey="Wen, Chih Chun" sort="Wen, Chih Chun" uniqKey="Wen C" first="Chih-Chun" last="Wen">Chih-Chun Wen</name><affiliation wicri:level="1"><nlm:aff id="aff1">Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung 404, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung 404</wicri:regionArea><wicri:noRegion>Taichung 404</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115</wicri:regionArea><wicri:noRegion>Taipei 115</wicri:noRegion></affiliation></author><author><name sortKey="Shyur, Lie Fen" sort="Shyur, Lie Fen" uniqKey="Shyur L" first="Lie-Fen" last="Shyur">Lie-Fen Shyur</name><affiliation wicri:level="1"><nlm:aff id="aff2">Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115</wicri:regionArea><wicri:noRegion>Taipei 115</wicri:noRegion></affiliation></author><author><name sortKey="Jan, Jia Tsrong" sort="Jan, Jia Tsrong" uniqKey="Jan J" first="Jia-Tsrong" last="Jan">Jia-Tsrong Jan</name><affiliation wicri:level="1"><nlm:aff id="aff3">Genomics Research Center, Academia Sinica, Taipei 115, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Genomics Research Center, Academia Sinica, Taipei 115</wicri:regionArea><wicri:noRegion>Taipei 115</wicri:noRegion></affiliation></author><author><name sortKey="Liang, Po Huang" sort="Liang, Po Huang" uniqKey="Liang P" first="Po-Huang" last="Liang">Po-Huang Liang</name><affiliation wicri:level="1"><nlm:aff id="aff4">Institute of Biological Chemistry, Academia Sinica, Taipei 115, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Institute of Biological Chemistry, Academia Sinica, Taipei 115</wicri:regionArea><wicri:noRegion>Taipei 115</wicri:noRegion></affiliation></author><author><name sortKey="Kuo, Chih Jung" sort="Kuo, Chih Jung" uniqKey="Kuo C" first="Chih-Jung" last="Kuo">Chih-Jung Kuo</name><affiliation wicri:level="1"><nlm:aff id="aff4">Institute of Biological Chemistry, Academia Sinica, Taipei 115, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Institute of Biological Chemistry, Academia Sinica, Taipei 115</wicri:regionArea><wicri:noRegion>Taipei 115</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="aff5">Department of Population Medicine and Diagnostic Science, Veterinary Medical Center, Cornell University, Ithaca, NY, 14853 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Population Medicine and Diagnostic Science, Veterinary Medical Center, Cornell University, Ithaca, NY</wicri:regionArea><orgName type="university">Université Cornell</orgName><placeName><settlement type="city">Ithaca (New York)</settlement><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Arulselvan, Palanisamy" sort="Arulselvan, Palanisamy" uniqKey="Arulselvan P" first="Palanisamy" last="Arulselvan">Palanisamy Arulselvan</name><affiliation wicri:level="1"><nlm:aff id="aff2">Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115</wicri:regionArea><wicri:noRegion>Taipei 115</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Jin Bin" sort="Wu, Jin Bin" uniqKey="Wu J" first="Jin-Bin" last="Wu">Jin-Bin Wu</name><affiliation wicri:level="1"><nlm:aff id="aff1">Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung 404, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung 404</wicri:regionArea><wicri:noRegion>Taichung 404</wicri:noRegion></affiliation></author><author><name sortKey="Kuo, Sheng Chu" sort="Kuo, Sheng Chu" uniqKey="Kuo S" first="Sheng-Chu" last="Kuo">Sheng-Chu Kuo</name><affiliation wicri:level="1"><nlm:aff id="aff1">Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung 404, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung 404</wicri:regionArea><wicri:noRegion>Taichung 404</wicri:noRegion></affiliation></author><author><name sortKey="Yang, Ning Sun" sort="Yang, Ning Sun" uniqKey="Yang N" first="Ning-Sun" last="Yang">Ning-Sun Yang</name><affiliation wicri:level="1"><nlm:aff id="aff2">Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115</wicri:regionArea><wicri:noRegion>Taipei 115</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of Traditional and Complementary Medicine</title><idno type="eISSN">2225-4110</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Development of anti-severe acute respiratory syndrome associated coronavirus (SARS-CoV) agents is pivotal to prevent the reemergence of the life-threatening disease, SARS. In this study, more than 200 extracts from Chinese medicinal herbs were evaluated for anti-SARS-CoV activities using a cell-based assay that measured SARS-CoV-induced cytopathogenic effect (CPE) <italic>in vitro</italic> on Vero E6 cells. Six herbal extracts, one each from Gentianae Radix (龍膽 lóng dǎn; the dried rhizome of <italic>Gentiana scabra</italic>), Dioscoreae Rhizoma (山藥 shān yào; the tuber of <italic>Dioscorea batatas</italic>), Cassiae Semen (決明子 jué míng zǐ; the dried seed of <italic>Cassia tora</italic>) and Loranthi Ramus (桑寄生 sāng jì shēng; the dried stem, with leaf of <italic>Taxillus chinensis</italic>) (designated as GSH, DBM, CTH and TCH, respectively), and two from Rhizoma Cibotii (狗脊 gǒu jǐ; the dried rhizome of <italic>Cibotium barometz</italic>) (designated as CBE and CBM), were found to be potent inhibitors of SARS-CoV at concentrations between 25 and 200 μg/ml. The concentrations of the six extracts needed to inhibit 50% of Vero E6 cell proliferation (CC<sub>50</sub>) and 50% of viral replication (EC<sub>50</sub>) were determined. The resulting selective index values (SI = CC<sub>50</sub>/EC<sub>50</sub>) of the most effective extracts CBE, GSH, DBM, CTH and TCH were > 59.4, > 57.5, > 62.1, > 59.4, and > 92.9, respectively. Among these extracts, CBM and DBM also showed significant inhibition of SARS-CoV 3CL protease activity with IC<sub>50</sub> values of 39 μg/ml and 44 μg/ml, respectively. Our findings suggest that these six herbal extracts may have potential as candidates for future development of anti-SARS therapeutics.</p><sec id="st1"><title></title><def-list><title>Abbreviations</title><def-item><term>SARS,</term><def><p>severe acute respiratory syndrome</p></def></def-item><def-item><term>CoV,</term><def><p>coronavirus</p></def></def-item><def-item><term>CPE,</term><def><p>cytopathogenic effect</p></def></def-item><def-item><term>TCM,</term><def><p>traditional Chinese medicine</p></def></def-item></def-list></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Amici, C" uniqKey="Amici C">C Amici</name></author><author><name sortKey="Di Coro, A" uniqKey="Di Coro A">A Di Coro</name></author><author><name sortKey="Ciucci, A" uniqKey="Ciucci A">A Ciucci</name></author><author><name sortKey="Chiappa, L" uniqKey="Chiappa L">L Chiappa</name></author><author><name sortKey="Castilletti, C" uniqKey="Castilletti C">C Castilletti</name></author><author><name sortKey="Martella, V" uniqKey="Martella V">V Martella</name></author><author><name sortKey="Decaro, N" uniqKey="Decaro N">N Decaro</name></author><author><name sortKey="Buonavoglia, C" uniqKey="Buonavoglia C">C Buonavoglia</name></author><author><name sortKey="Capobianchi, M R" uniqKey="Capobianchi M">M.R Capobianchi</name></author><author><name sortKey="Santoro, M G" uniqKey="Santoro M">M.G Santoro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, C J" uniqKey="Chen C">C.J Chen</name></author><author><name sortKey="Michaelis, M" uniqKey="Michaelis M">M Michaelis</name></author><author><name sortKey="Hsu, H K" uniqKey="Hsu H">H.K Hsu</name></author><author><name sortKey="Tsai, C C" uniqKey="Tsai C">C.C Tsai</name></author><author><name sortKey="Yang, K D" uniqKey="Yang K">K.D Yang</name></author><author><name sortKey="Wu, Y C" uniqKey="Wu Y">Y.C Wu</name></author><author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J Cinatl</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W Doerr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, C N" uniqKey="Chen C">C.N Chen</name></author><author><name sortKey="Lin, C P" uniqKey="Lin C">C.P Lin</name></author><author><name sortKey="Huang, K K" uniqKey="Huang K">K.K Huang</name></author><author><name sortKey="Chen, W C" uniqKey="Chen W">W.C Chen</name></author><author><name sortKey="Hsieh, H P" uniqKey="Hsieh H">H.P Hsieh</name></author><author><name sortKey="Liang, P H" uniqKey="Liang P">P.H Liang</name></author><author><name sortKey="Hsu, J T" uniqKey="Hsu J">J.T Hsu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, Y H" uniqKey="Chen Y">Y.H Chen</name></author><author><name sortKey="Chen, A P" uniqKey="Chen A">A.P Chen</name></author><author><name sortKey="Chen, C T" uniqKey="Chen C">C.T Chen</name></author><author><name sortKey="Wang, A H" uniqKey="Wang A">A.H Wang</name></author><author><name sortKey="Liang, P H" uniqKey="Liang P">P.H Liang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cho, I J" uniqKey="Cho I">I.J Cho</name></author><author><name sortKey="Lee, C" uniqKey="Lee C">C Lee</name></author><author><name sortKey="Ha, T Y" uniqKey="Ha T">T.Y Ha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chueh, F S" uniqKey="Chueh F">F.S Chueh</name></author><author><name sortKey="Chen, C C" uniqKey="Chen C">C.C Chen</name></author><author><name sortKey="Sagare, A P" uniqKey="Sagare A">A.P Sagare</name></author><author><name sortKey="Tsay, H S" uniqKey="Tsay H">H.S Tsay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J Cinatl</name></author><author><name sortKey="Michaelis, M" uniqKey="Michaelis M">M Michaelis</name></author><author><name sortKey="Hoever, G" uniqKey="Hoever G">G Hoever</name></author><author><name sortKey="Preiser, W" uniqKey="Preiser W">W Preiser</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W Doerr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J Cinatl</name></author><author><name sortKey="Morgenstern, B" uniqKey="Morgenstern B">B Morgenstern</name></author><author><name sortKey="Bauer, G" uniqKey="Bauer G">G Bauer</name></author><author><name sortKey="Chandra, P" uniqKey="Chandra P">P Chandra</name></author><author><name sortKey="Rabenau, H" uniqKey="Rabenau H">H Rabenau</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W Doerr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cleri, D J" uniqKey="Cleri D">D.J Cleri</name></author><author><name sortKey="Ricketti, A J" uniqKey="Ricketti A">A.J Ricketti</name></author><author><name sortKey="Vernaleo, J R" uniqKey="Vernaleo J">J.R Vernaleo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cuong, N X" uniqKey="Cuong N">N.X Cuong</name></author><author><name sortKey="Minh, C V" uniqKey="Minh C">C.V Minh</name></author><author><name sortKey="Kiem, P V" uniqKey="Kiem P">P.V Kiem</name></author><author><name sortKey="Huong, H T" uniqKey="Huong H">H.T Huong</name></author><author><name sortKey="Ban, N K" uniqKey="Ban N">N.K Ban</name></author><author><name sortKey="Nhiem, N X" uniqKey="Nhiem N">N.X Nhiem</name></author><author><name sortKey="Tung, N H" uniqKey="Tung N">N.H Tung</name></author><author><name sortKey="Jung, J W" uniqKey="Jung J">J.W Jung</name></author><author><name sortKey="Kim, H J" uniqKey="Kim H">H.J Kim</name></author><author><name sortKey="Kim, S Y" uniqKey="Kim S">S.Y Kim</name></author><author><name sortKey="Kim, J A" uniqKey="Kim J">J.A Kim</name></author><author><name sortKey="Kim, Y H" uniqKey="Kim Y">Y.H Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Clercq, E" uniqKey="De Clercq E">E De Clercq</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drosten, C" uniqKey="Drosten C">C Drosten</name></author><author><name sortKey="Gunther, S" uniqKey="Gunther S">S Gunther</name></author><author><name sortKey="Preiser, W" uniqKey="Preiser W">W Preiser</name></author><author><name sortKey="Van Der Werf, S" uniqKey="Van Der Werf S">S van der Werf</name></author><author><name sortKey="Brodt, H R" uniqKey="Brodt H">H.R Brodt</name></author><author><name sortKey="Becker, S" uniqKey="Becker S">S Becker</name></author><author><name sortKey="Rabenau, H" uniqKey="Rabenau H">H Rabenau</name></author><author><name sortKey="Panning, M" uniqKey="Panning M">M Panning</name></author><author><name sortKey="Kolesnikova, L" uniqKey="Kolesnikova L">L Kolesnikova</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A Fouchier</name></author><author><name sortKey="Berger, A" uniqKey="Berger A">A Berger</name></author><author><name sortKey="Burguiere, A M" uniqKey="Burguiere A">A.M Burguiere</name></author><author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J Cinatl</name></author><author><name sortKey="Eickmann, M" uniqKey="Eickmann M">M Eickmann</name></author><author><name sortKey="Escriou, N" uniqKey="Escriou N">N Escriou</name></author><author><name sortKey="Grywna, K" uniqKey="Grywna K">K Grywna</name></author><author><name sortKey="Kramme, S" uniqKey="Kramme S">S Kramme</name></author><author><name sortKey="Manuguerra, J C" uniqKey="Manuguerra J">J.C Manuguerra</name></author><author><name sortKey="Muller, S" uniqKey="Muller S">S Muller</name></author><author><name sortKey="Rickerts, V" uniqKey="Rickerts V">V Rickerts</name></author><author><name sortKey="Sturmer, M" uniqKey="Sturmer M">M Sturmer</name></author><author><name sortKey="Vieth, S" uniqKey="Vieth S">S Vieth</name></author><author><name sortKey="Klenk, H D" uniqKey="Klenk H">H.D Klenk</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D Osterhaus</name></author><author><name sortKey="Schmitz, H" uniqKey="Schmitz H">H Schmitz</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W Doerr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gallagher, T M" uniqKey="Gallagher T">T.M Gallagher</name></author><author><name sortKey="Buchmeier, M J" uniqKey="Buchmeier M">M.J Buchmeier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Groneberg, D A" uniqKey="Groneberg D">D.A Groneberg</name></author><author><name sortKey="Poutanen, S M" uniqKey="Poutanen S">S.M Poutanen</name></author><author><name sortKey="Low, D E" uniqKey="Low D">D.E Low</name></author><author><name sortKey="Lode, H" uniqKey="Lode H">H Lode</name></author><author><name sortKey="Welte, T" uniqKey="Welte T">T Welte</name></author><author><name sortKey="Zabel, P" uniqKey="Zabel P">P Zabel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hatano, T" uniqKey="Hatano T">T Hatano</name></author><author><name sortKey="Uebayashi, H" uniqKey="Uebayashi H">H Uebayashi</name></author><author><name sortKey="Ito, H" uniqKey="Ito H">H Ito</name></author><author><name sortKey="Shiota, S" uniqKey="Shiota S">S Shiota</name></author><author><name sortKey="Tsuchiya, T" uniqKey="Tsuchiya T">T Tsuchiya</name></author><author><name sortKey="Yoshida, T" uniqKey="Yoshida T">T Yoshida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoever, G" uniqKey="Hoever G">G Hoever</name></author><author><name sortKey="Baltina, L" uniqKey="Baltina L">L Baltina</name></author><author><name sortKey="Michaelis, M" uniqKey="Michaelis M">M Michaelis</name></author><author><name sortKey="Kondratenko, R" uniqKey="Kondratenko R">R Kondratenko</name></author><author><name sortKey="Baltina, L" uniqKey="Baltina L">L Baltina</name></author><author><name sortKey="Tolstikov, G A" uniqKey="Tolstikov G">G.A Tolstikov</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W Doerr</name></author><author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J Cinatl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Holmes, K V" uniqKey="Holmes K">K.V Holmes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hyun, S K" uniqKey="Hyun S">S.K Hyun</name></author><author><name sortKey="Lee, H" uniqKey="Lee H">H Lee</name></author><author><name sortKey="Kang, S S" uniqKey="Kang S">S.S Kang</name></author><author><name sortKey="Chung, H Y" uniqKey="Chung H">H.Y Chung</name></author><author><name sortKey="Choi, J S" uniqKey="Choi J">J.S Choi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jiang, W X" uniqKey="Jiang W">W.X Jiang</name></author><author><name sortKey="Xue, B Y" uniqKey="Xue B">B.Y Xue</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jin, M" uniqKey="Jin M">M Jin</name></author><author><name sortKey="Suh, S J" uniqKey="Suh S">S.J Suh</name></author><author><name sortKey="Yang, J H" uniqKey="Yang J">J.H Yang</name></author><author><name sortKey="Lu, Y" uniqKey="Lu Y">Y Lu</name></author><author><name sortKey="Kim, S J" uniqKey="Kim S">S.J Kim</name></author><author><name sortKey="Kwon, S" uniqKey="Kwon S">S Kwon</name></author><author><name sortKey="Jo, T H" uniqKey="Jo T">T.H Jo</name></author><author><name sortKey="Kim, J W" uniqKey="Kim J">J.W Kim</name></author><author><name sortKey="Park, Y I" uniqKey="Park Y">Y.I Park</name></author><author><name sortKey="Ahn, G W" uniqKey="Ahn G">G.W Ahn</name></author><author><name sortKey="Lee, C K" uniqKey="Lee C">C.K Lee</name></author><author><name sortKey="Kim, C H" uniqKey="Kim C">C.H Kim</name></author><author><name sortKey="Son, J K" uniqKey="Son J">J.K Son</name></author><author><name sortKey="Son, K H" uniqKey="Son K">K.H Son</name></author><author><name sortKey="Chang, H W" uniqKey="Chang H">H.W Chang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kakuda, R" uniqKey="Kakuda R">R Kakuda</name></author><author><name sortKey="Iijima, T" uniqKey="Iijima T">T Iijima</name></author><author><name sortKey="Yaoita, Y" uniqKey="Yaoita Y">Y Yaoita</name></author><author><name sortKey="Machida, K" uniqKey="Machida K">K Machida</name></author><author><name sortKey="Kikuchi, M" uniqKey="Kikuchi M">M Kikuchi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, H Y" uniqKey="Kim H">H.Y Kim</name></author><author><name sortKey="Eo, E Y" uniqKey="Eo E">E.Y Eo</name></author><author><name sortKey="Park, H" uniqKey="Park H">H Park</name></author><author><name sortKey="Kim, Y C" uniqKey="Kim Y">Y.C Kim</name></author><author><name sortKey="Park, S" uniqKey="Park S">S Park</name></author><author><name sortKey="Shin, H J" uniqKey="Shin H">H.J Shin</name></author><author><name sortKey="Kim, K" uniqKey="Kim K">K Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, J A" uniqKey="Kim J">J.A Kim</name></author><author><name sortKey="Son, N S" uniqKey="Son N">N.S Son</name></author><author><name sortKey="Son, J K" uniqKey="Son J">J.K Son</name></author><author><name sortKey="Jahng, Y" uniqKey="Jahng Y">Y Jahng</name></author><author><name sortKey="Chang, H W" uniqKey="Chang H">H.W Chang</name></author><author><name sortKey="Jang, T S" uniqKey="Jang T">T.S Jang</name></author><author><name sortKey="Na, M" uniqKey="Na M">M Na</name></author><author><name sortKey="Lee, S H" uniqKey="Lee S">S.H Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Y M" uniqKey="Kim Y">Y.M Kim</name></author><author><name sortKey="Lee, C H" uniqKey="Lee C">C.H Lee</name></author><author><name sortKey="Kim, H G" uniqKey="Kim H">H.G Kim</name></author><author><name sortKey="Lee, H S" uniqKey="Lee H">H.S Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kliger, Y" uniqKey="Kliger Y">Y Kliger</name></author><author><name sortKey="Levanon, E Y" uniqKey="Levanon E">E.Y Levanon</name></author><author><name sortKey="Gerber, D" uniqKey="Gerber D">D Gerber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ksiazek, T G" uniqKey="Ksiazek T">T.G Ksiazek</name></author><author><name sortKey="Erdman, D" uniqKey="Erdman D">D Erdman</name></author><author><name sortKey="Goldsmith, C S" uniqKey="Goldsmith C">C.S Goldsmith</name></author><author><name sortKey="Zaki, S R" uniqKey="Zaki S">S.R Zaki</name></author><author><name sortKey="Peret, T" uniqKey="Peret T">T Peret</name></author><author><name sortKey="Emery, S" uniqKey="Emery S">S Emery</name></author><author><name sortKey="Tong, S" uniqKey="Tong S">S Tong</name></author><author><name sortKey="Urbani, C" uniqKey="Urbani C">C Urbani</name></author><author><name sortKey="Comer, J A" uniqKey="Comer J">J.A Comer</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W Lim</name></author><author><name sortKey="Rollin, P E" uniqKey="Rollin P">P.E Rollin</name></author><author><name sortKey="Dowell, S F" uniqKey="Dowell S">S.F Dowell</name></author><author><name sortKey="Ling, A E" uniqKey="Ling A">A.E Ling</name></author><author><name sortKey="Humphrey, C D" uniqKey="Humphrey C">C.D Humphrey</name></author><author><name sortKey="Shieh, W J" uniqKey="Shieh W">W.J Shieh</name></author><author><name sortKey="Guarner, J" uniqKey="Guarner J">J Guarner</name></author><author><name sortKey="Paddock, C D" uniqKey="Paddock C">C.D Paddock</name></author><author><name sortKey="Rota, P" uniqKey="Rota P">P Rota</name></author><author><name sortKey="Fields, B" uniqKey="Fields B">B Fields</name></author><author><name sortKey="De Risi, J" uniqKey="De Risi J">J De Risi</name></author><author><name sortKey="Yang, J Y" uniqKey="Yang J">J.Y Yang</name></author><author><name sortKey="Cox, N" uniqKey="Cox N">N Cox</name></author><author><name sortKey="Hughes, J M" uniqKey="Hughes J">J.M Hughes</name></author><author><name sortKey="Le Duc, J W" uniqKey="Le Duc J">J.W Le Duc</name></author><author><name sortKey="Bellini, W J" uniqKey="Bellini W">W.J Bellini</name></author><author><name sortKey="Anderson, L J" uniqKey="Anderson L">L.J Anderson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T Kuiken</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A Fouchier</name></author><author><name sortKey="Schutten, M" uniqKey="Schutten M">M Schutten</name></author><author><name sortKey="Rimmelzwaan, G F" uniqKey="Rimmelzwaan G">G.F Rimmelzwaan</name></author><author><name sortKey="Van Amerongen, G" uniqKey="Van Amerongen G">G van Amerongen</name></author><author><name sortKey="Van Riel, D" uniqKey="Van Riel D">D van Riel</name></author><author><name sortKey="Laman, J D" uniqKey="Laman J">J.D Laman</name></author><author><name sortKey="De Jong, T" uniqKey="De Jong T">T de Jong</name></author><author><name sortKey="Van Doornum, G" uniqKey="Van Doornum G">G van Doornum</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W Lim</name></author><author><name sortKey="Ling, A E" uniqKey="Ling A">A.E Ling</name></author><author><name sortKey="Chan, P K" uniqKey="Chan P">P.K Chan</name></author><author><name sortKey="Tam, J S" uniqKey="Tam J">J.S Tam</name></author><author><name sortKey="Zambon, M C" uniqKey="Zambon M">M.C Zambon</name></author><author><name sortKey="Gopal, R" uniqKey="Gopal R">R Gopal</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C Drosten</name></author><author><name sortKey="Van Der Werf, S" uniqKey="Van Der Werf S">S van der Werf</name></author><author><name sortKey="Escriou, N" uniqKey="Escriou N">N Escriou</name></author><author><name sortKey="Manuguerra, J C" uniqKey="Manuguerra J">J.C Manuguerra</name></author><author><name sortKey="Stohr, K" uniqKey="Stohr K">K Stohr</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S Peiris</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D Osterhaus</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuo, C J" uniqKey="Kuo C">C.J Kuo</name></author><author><name sortKey="Chi, Y H" uniqKey="Chi Y">Y.H Chi</name></author><author><name sortKey="Hsu, J T" uniqKey="Hsu J">J.T Hsu</name></author><author><name sortKey="Liang, P H" uniqKey="Liang P">P.H Liang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lai, H Y" uniqKey="Lai H">H.Y Lai</name></author><author><name sortKey="Lim, Y Y" uniqKey="Lim Y">Y.Y Lim</name></author><author><name sortKey="Tan, S P" uniqKey="Tan S">S.P Tan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lai, S T" uniqKey="Lai S">S.T Lai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, K M" uniqKey="Lau K">K.M Lau</name></author><author><name sortKey="Lee, K M" uniqKey="Lee K">K.M Lee</name></author><author><name sortKey="Koon, C M" uniqKey="Koon C">C.M Koon</name></author><author><name sortKey="Cheung, C S" uniqKey="Cheung C">C.S Cheung</name></author><author><name sortKey="Lau, C P" uniqKey="Lau C">C.P Lau</name></author><author><name sortKey="Ho, H M" uniqKey="Ho H">H.M Ho</name></author><author><name sortKey="Lee, M Y" uniqKey="Lee M">M.Y Lee</name></author><author><name sortKey="Au, S W" uniqKey="Au S">S.W Au</name></author><author><name sortKey="Cheng, C H" uniqKey="Cheng C">C.H Cheng</name></author><author><name sortKey="Lau, C B" uniqKey="Lau C">C.B Lau</name></author><author><name sortKey="Tsui, S K" uniqKey="Tsui S">S.K Tsui</name></author><author><name sortKey="Wan, D C" uniqKey="Wan D">D.C Wan</name></author><author><name sortKey="Waye, M M" uniqKey="Waye M">M.M Waye</name></author><author><name sortKey="Wong, K B" uniqKey="Wong K">K.B Wong</name></author><author><name sortKey="Wong, C K" uniqKey="Wong C">C.K Wong</name></author><author><name sortKey="Lam, C W" uniqKey="Lam C">C.W Lam</name></author><author><name sortKey="Leung, P C" uniqKey="Leung P">P.C Leung</name></author><author><name sortKey="Fung, K P" uniqKey="Fung K">K.P Fung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, S Y" uniqKey="Li S">S.Y Li</name></author><author><name sortKey="Chen, C" uniqKey="Chen C">C Chen</name></author><author><name sortKey="Zhang, H Q" uniqKey="Zhang H">H.Q Zhang</name></author><author><name sortKey="Guo, H Y" uniqKey="Guo H">H.Y Guo</name></author><author><name sortKey="Wang, H" uniqKey="Wang H">H Wang</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L Wang</name></author><author><name sortKey="Zhang, X" uniqKey="Zhang X">X Zhang</name></author><author><name sortKey="Hua, S N" uniqKey="Hua S">S.N Hua</name></author><author><name sortKey="Yu, J" uniqKey="Yu J">J Yu</name></author><author><name sortKey="Xiao, P G" uniqKey="Xiao P">P.G Xiao</name></author><author><name sortKey="Li, R S" uniqKey="Li R">R.S Li</name></author><author><name sortKey="Tan, X" uniqKey="Tan X">X Tan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, C W" uniqKey="Lin C">C.W Lin</name></author><author><name sortKey="Tsai, F J" uniqKey="Tsai F">F.J Tsai</name></author><author><name sortKey="Tsai, C H" uniqKey="Tsai C">C.H Tsai</name></author><author><name sortKey="Lai, C C" uniqKey="Lai C">C.C Lai</name></author><author><name sortKey="Wan, L" uniqKey="Wan L">L Wan</name></author><author><name sortKey="Ho, T Y" uniqKey="Ho T">T.Y Ho</name></author><author><name sortKey="Hsieh, C C" uniqKey="Hsieh C">C.C Hsieh</name></author><author><name sortKey="Chao, P D" uniqKey="Chao P">P.D Chao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S Peiris</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y Yuen</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D Osterhaus</name></author><author><name sortKey="Stohr, K" uniqKey="Stohr K">K Stohr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ryu, Y B" uniqKey="Ryu Y">Y.B Ryu</name></author><author><name sortKey="Jeong, H J" uniqKey="Jeong H">H.J Jeong</name></author><author><name sortKey="Kim, J H" uniqKey="Kim J">J.H Kim</name></author><author><name sortKey="Kim, Y M" uniqKey="Kim Y">Y.M Kim</name></author><author><name sortKey="Park, J Y" uniqKey="Park J">J.Y Park</name></author><author><name sortKey="Kim, D" uniqKey="Kim D">D Kim</name></author><author><name sortKey="Nguyen, T T" uniqKey="Nguyen T">T.T Nguyen</name></author><author><name sortKey="Park, S J" uniqKey="Park S">S.J Park</name></author><author><name sortKey="Chang, J S" uniqKey="Chang J">J.S Chang</name></author><author><name sortKey="Park, K H" uniqKey="Park K">K.H Park</name></author><author><name sortKey="Rho, M C" uniqKey="Rho M">M.C Rho</name></author><author><name sortKey="Lee, W S" uniqKey="Lee W">W.S Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="So, L K" uniqKey="So L">L.K So</name></author><author><name sortKey="Lau, A C" uniqKey="Lau A">A.C Lau</name></author><author><name sortKey="Yam, L Y" uniqKey="Yam L">L.Y Yam</name></author><author><name sortKey="Cheung, T M" uniqKey="Cheung T">T.M Cheung</name></author><author><name sortKey="Poon, E" uniqKey="Poon E">E Poon</name></author><author><name sortKey="Yung, R W" uniqKey="Yung R">R.W Yung</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stadler, K" uniqKey="Stadler K">K Stadler</name></author><author><name sortKey="Masignani, V" uniqKey="Masignani V">V Masignani</name></author><author><name sortKey="Eickmann, M" uniqKey="Eickmann M">M Eickmann</name></author><author><name sortKey="Becker, S" uniqKey="Becker S">S Becker</name></author><author><name sortKey="Abrignani, S" uniqKey="Abrignani S">S Abrignani</name></author><author><name sortKey="Klenk, H D" uniqKey="Klenk H">H.D Klenk</name></author><author><name sortKey="Rappuoli, R" uniqKey="Rappuoli R">R Rappuoli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stroher, U" uniqKey="Stroher U">U Stroher</name></author><author><name sortKey="Di Caro, A" uniqKey="Di Caro A">A Di Caro</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name></author><author><name sortKey="Strong, J E" uniqKey="Strong J">J.E Strong</name></author><author><name sortKey="Aoki, F" uniqKey="Aoki F">F Aoki</name></author><author><name sortKey="Plummer, F" uniqKey="Plummer F">F Plummer</name></author><author><name sortKey="Jones, S M" uniqKey="Jones S">S.M Jones</name></author><author><name sortKey="Feldmann, H" uniqKey="Feldmann H">H Feldmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Su, P F" uniqKey="Su P">P.F Su</name></author><author><name sortKey="Li, C J" uniqKey="Li C">C.J Li</name></author><author><name sortKey="Hsu, C C" uniqKey="Hsu C">C.C Hsu</name></author><author><name sortKey="Benson, S" uniqKey="Benson S">S Benson</name></author><author><name sortKey="Wang, S Y" uniqKey="Wang S">S.Y Wang</name></author><author><name sortKey="Aravindaram, K" uniqKey="Aravindaram K">K Aravindaram</name></author><author><name sortKey="Chan, S I" uniqKey="Chan S">S.I Chan</name></author><author><name sortKey="Wu, S H" uniqKey="Wu S">S.H Wu</name></author><author><name sortKey="Yang, F L" uniqKey="Yang F">F.L Yang</name></author><author><name sortKey="Huang, C H" uniqKey="Huang C">C.H Huang</name></author><author><name sortKey="Shyur, L F" uniqKey="Shyur L">L.F Shyur</name></author><author><name sortKey="Yang, N S" uniqKey="Yang N">N.S Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Su, P F" uniqKey="Su P">P.F Su</name></author><author><name sortKey="Staniforth, V" uniqKey="Staniforth V">V Staniforth</name></author><author><name sortKey="Li, C J" uniqKey="Li C">C.J Li</name></author><author><name sortKey="Wang, C Y" uniqKey="Wang C">C.Y Wang</name></author><author><name sortKey="Chiao, M T" uniqKey="Chiao M">M.T Chiao</name></author><author><name sortKey="Wang, S Y" uniqKey="Wang S">S.Y Wang</name></author><author><name sortKey="Shyur, L F" uniqKey="Shyur L">L.F Shyur</name></author><author><name sortKey="Yang, N S" uniqKey="Yang N">N.S Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tan, E L" uniqKey="Tan E">E.L Tan</name></author><author><name sortKey="Ooi, E E" uniqKey="Ooi E">E.E Ooi</name></author><author><name sortKey="Lin, C Y" uniqKey="Lin C">C.Y Lin</name></author><author><name sortKey="Tan, H C" uniqKey="Tan H">H.C Tan</name></author><author><name sortKey="Ling, A E" uniqKey="Ling A">A.E Ling</name></author><author><name sortKey="Lim, B" uniqKey="Lim B">B Lim</name></author><author><name sortKey="Stanton, L W" uniqKey="Stanton L">L.W Stanton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Deng, M" uniqKey="Deng M">M Deng</name></author><author><name sortKey="Zhang, S Y" uniqKey="Zhang S">S.Y Zhang</name></author><author><name sortKey="Zhou, Z K" uniqKey="Zhou Z">Z.K Zhou</name></author><author><name sortKey="Tian, W X" uniqKey="Tian W">W.X Tian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Zhang, S Y" uniqKey="Zhang S">S.Y Zhang</name></author><author><name sortKey="Ma, X F" uniqKey="Ma X">X.F Ma</name></author><author><name sortKey="Tian, W X" uniqKey="Tian W">W.X Tian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wen, C C" uniqKey="Wen C">C.C Wen</name></author><author><name sortKey="Kuo, Y H" uniqKey="Kuo Y">Y.H Kuo</name></author><author><name sortKey="Jan, J T" uniqKey="Jan J">J.T Jan</name></author><author><name sortKey="Liang, P H" uniqKey="Liang P">P.H Liang</name></author><author><name sortKey="Wang, S Y" uniqKey="Wang S">S.Y Wang</name></author><author><name sortKey="Liu, H G" uniqKey="Liu H">H.G Liu</name></author><author><name sortKey="Lee, C K" uniqKey="Lee C">C.K Lee</name></author><author><name sortKey="Chang, S T" uniqKey="Chang S">S.T Chang</name></author><author><name sortKey="Kuo, C J" uniqKey="Kuo C">C.J Kuo</name></author><author><name sortKey="Lee, S S" uniqKey="Lee S">S.S Lee</name></author><author><name sortKey="Hou, C C" uniqKey="Hou C">C.C Hou</name></author><author><name sortKey="Hsiao, P W" uniqKey="Hsiao P">P.W Hsiao</name></author><author><name sortKey="Chien, S C" uniqKey="Chien S">S.C Chien</name></author><author><name sortKey="Shyur, L F" uniqKey="Shyur L">L.F Shyur</name></author><author><name sortKey="Yang, N S" uniqKey="Yang N">N.S Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, C H" uniqKey="Wu C">C.H Wu</name></author><author><name sortKey="Yen, G C" uniqKey="Yen G">G.C Yen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, C Y" uniqKey="Wu C">C.Y Wu</name></author><author><name sortKey="Jan, J T" uniqKey="Jan J">J.T Jan</name></author><author><name sortKey="Ma, S H" uniqKey="Ma S">S.H Ma</name></author><author><name sortKey="Kuo, C J" uniqKey="Kuo C">C.J Kuo</name></author><author><name sortKey="Juan, H F" uniqKey="Juan H">H.F Juan</name></author><author><name sortKey="Cheng, Y S" uniqKey="Cheng Y">Y.S Cheng</name></author><author><name sortKey="Hsu, H H" uniqKey="Hsu H">H.H Hsu</name></author><author><name sortKey="Huang, H C" uniqKey="Huang H">H.C Huang</name></author><author><name sortKey="Wu, D" uniqKey="Wu D">D Wu</name></author><author><name sortKey="Brik, A" uniqKey="Brik A">A Brik</name></author><author><name sortKey="Liang, F S" uniqKey="Liang F">F.S Liang</name></author><author><name sortKey="Liu, R S" uniqKey="Liu R">R.S Liu</name></author><author><name sortKey="Fang, J M" uniqKey="Fang J">J.M Fang</name></author><author><name sortKey="Chen, S T" uniqKey="Chen S">S.T Chen</name></author><author><name sortKey="Liang, P H" uniqKey="Liang P">P.H Liang</name></author><author><name sortKey="Wong, C H" uniqKey="Wong C">C.H Wong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yi, L" uniqKey="Yi L">L Yi</name></author><author><name sortKey="Li, Z" uniqKey="Li Z">Z Li</name></author><author><name sortKey="Yuan, K" uniqKey="Yuan K">K Yuan</name></author><author><name sortKey="Qu, X" uniqKey="Qu X">X Qu</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J Chen</name></author><author><name sortKey="Wang, G" uniqKey="Wang G">G Wang</name></author><author><name sortKey="Zhang, H" uniqKey="Zhang H">H Zhang</name></author><author><name sortKey="Luo, H" uniqKey="Luo H">H Luo</name></author><author><name sortKey="Zhu, L" uniqKey="Zhu L">L Zhu</name></author><author><name sortKey="Jiang, P" uniqKey="Jiang P">P Jiang</name></author><author><name sortKey="Chen, L" uniqKey="Chen L">L Chen</name></author><author><name sortKey="Shen, Y" uniqKey="Shen Y">Y Shen</name></author><author><name sortKey="Luo, M" uniqKey="Luo M">M Luo</name></author><author><name sortKey="Zuo, G" uniqKey="Zuo G">G Zuo</name></author><author><name sortKey="Hu, J" uniqKey="Hu J">J Hu</name></author><author><name sortKey="Duan, D" uniqKey="Duan D">D Duan</name></author><author><name sortKey="Nie, Y" uniqKey="Nie Y">Y Nie</name></author><author><name sortKey="Shi, X" uniqKey="Shi X">X Shi</name></author><author><name sortKey="Wang, W" uniqKey="Wang W">W Wang</name></author><author><name sortKey="Han, Y" uniqKey="Han Y">Y Han</name></author><author><name sortKey="Li, T" uniqKey="Li T">T Li</name></author><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y Liu</name></author><author><name sortKey="Ding, M" uniqKey="Ding M">M Ding</name></author><author><name sortKey="Deng, H" uniqKey="Deng H">H Deng</name></author><author><name sortKey="Xu, X" uniqKey="Xu X">X Xu</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Taïwan</li><li>États-Unis</li></country><region><li>État de New York</li></region><settlement><li>Ithaca (New York)</li></settlement><orgName><li>Université Cornell</li></orgName></list><tree><country name="Taïwan"><noRegion><name sortKey="Wen, Chih Chun" sort="Wen, Chih Chun" uniqKey="Wen C" first="Chih-Chun" last="Wen">Chih-Chun Wen</name></noRegion><name sortKey="Arulselvan, Palanisamy" sort="Arulselvan, Palanisamy" uniqKey="Arulselvan P" first="Palanisamy" last="Arulselvan">Palanisamy Arulselvan</name><name sortKey="Jan, Jia Tsrong" sort="Jan, Jia Tsrong" uniqKey="Jan J" first="Jia-Tsrong" last="Jan">Jia-Tsrong Jan</name><name sortKey="Kuo, Chih Jung" sort="Kuo, Chih Jung" uniqKey="Kuo C" first="Chih-Jung" last="Kuo">Chih-Jung Kuo</name><name sortKey="Kuo, Sheng Chu" sort="Kuo, Sheng Chu" uniqKey="Kuo S" first="Sheng-Chu" last="Kuo">Sheng-Chu Kuo</name><name sortKey="Liang, Po Huang" sort="Liang, Po Huang" uniqKey="Liang P" first="Po-Huang" last="Liang">Po-Huang Liang</name><name sortKey="Shyur, Lie Fen" sort="Shyur, Lie Fen" uniqKey="Shyur L" first="Lie-Fen" last="Shyur">Lie-Fen Shyur</name><name sortKey="Wen, Chih Chun" sort="Wen, Chih Chun" uniqKey="Wen C" first="Chih-Chun" last="Wen">Chih-Chun Wen</name><name sortKey="Wu, Jin Bin" sort="Wu, Jin Bin" uniqKey="Wu J" first="Jin-Bin" last="Wu">Jin-Bin Wu</name><name sortKey="Yang, Ning Sun" sort="Yang, Ning Sun" uniqKey="Yang N" first="Ning-Sun" last="Yang">Ning-Sun Yang</name></country><country name="États-Unis"><region name="État de New York"><name sortKey="Kuo, Chih Jung" sort="Kuo, Chih Jung" uniqKey="Kuo C" first="Chih-Jung" last="Kuo">Chih-Jung Kuo</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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